What is the true remission in rheumatoid arthritis?

为了研究类风湿关节炎（RA）的真正缓解，我们研究了预后不良的早期RA因素。使用合成疾病改善抗风湿药物治疗可减少未分化关节炎的RA进展。mri证实的骨水肿的显著改善可能与防止结构损伤有关(rs=0。65, p < 0。在采用严格控制方法管理的早期RA患者中，持续缓解12个月。RA患者外周血调节性T细胞频率与疾病活动度评分、CRP、ESR呈负相关。RA缓解期患者的调节性T细胞频率与健康对照相似。

To investigate the true remission in rheumatoid arthritis(RA), we studied very early RA with poor prognosis factors. Treatment with synthetic disease-modifying anti-rheumatic drugs reduced RA progression from undifferentiated arthritis. Significant improvement in MRI-proven bone edema may be associated with protection against structural damage(rs=0. 65, p<0. 05) and persistent remission during 12 months in very early RA patients managed using the tight control approach. The frequency of peripheral blood regulatory T cells in patients with RA negatively correlated with disease activity score, CRP and ESR. The regulatory T cell frequency of patients with RA in remission was similar to that of healthy controls.