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A role of nuclear import activity on the proliferation of cutaneous diseases

A role of nuclear import activity on the proliferation of cutaneous diseases
核输入活动对皮肤疾病扩散的作用
批准号:
22791070
负责人:
UMEGAKI Noriko
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
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英文摘要
Detection and analysis of target proteins imported by karyopherin alpha 2(KPNA2) in HaCaT cells using tandem affinity purification method and mass spectrometry to investigate the roles of KPNA2 in the cell growth. Immunohistochemical staining using anti-KPNA2 antibody was performed in the skin diseases including psoriasis and squamous cell carcinomas to demonstrate the relation ship between KPNA2 and keratinocyte proliferation.
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Pregnancy and childbirth in three mothers with recessive dystrophic epidermolysis bullosa
三名隐性营养不良性大疱性表皮松解症母亲的妊娠和分娩
DOI: --
发表时间: 2012
期刊: Clinical and experimental dermatology
影响因子: 4.1
作者: [Hanafusa T, Tamai K, Umegaki N, Yamaguchi Y, Fukuda S, Nishikawa Y, Yaegashi N, Okuyama R, McGrath JA, Katayama I]
通讯作者: Katayama I
PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia
骨髓中的 PDGFRα 阳性细胞被高迁移率族蛋白 1 (HMGB1) 动员以再生受损的上皮细胞
DOI: --
发表时间: 2011
期刊: Proc Natl Acad Sci
影响因子: --
作者: [Tamai K, Yamazaki T, Chino T, Ishii M, Otsuru S, Kikuchi Y, Iinuma S, Saga K, Nimura K, Shimbo T, Umegaki N, Katayama I, Miyazaki J, Takeda J, McGrath JA, Uitto J, Kaneda Y]
通讯作者: Kaneda Y
PDGFR alpha-positive cells in bone marrow are mobilized by high mobility group box 1(HMGB1) to regenerate injured epithelia
骨髓中的 PDGFR α 阳性细胞被高迁移率族蛋白 1 (HMGB1) 动员以再生受损的上皮细胞
DOI: --
发表时间: 2011
期刊: Proc Natl Acad Sci
影响因子: --
作者: [Tamai K, Yamazaki T, Chino T, Ishii M, Otsuru S, Kikuchi Y, Iinuma S, Saga K, Nimura K, Shimbo T, Umegaki N, Katayama I, Miyazaki J, Takeda J, McGrath JA, Uitto J, Kaneda Y]
通讯作者: Kaneda Y
Vorner type palmoplantar keratoderma: novel KRT9 mutation associated with knuckle pad-like lesion and recurrent mutation causing digital mutilation.
Vorner 型掌跖角化病:与指节垫样病变相关的新型 KRT9 突变和导致指残的复发突变。
DOI: --
发表时间: 2011
期刊: Br J Dermatol
影响因子: --
作者: [Umegaki N, Nakano H, Tamai K, Mitsuhashi Y, Akasaka E, Sawamura D, Katayama I]
通讯作者: Katayama I
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    A role of nuclear import activity on the pathomechanism of cutaneous diseases
    • 批准号:
      20790800
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.75万
    • 财政年份:
      2008
    • 负责人:
      UMEGAKI Noriko
    • 依托单位:
    海外基金