Angiogenesis, neurogenesis and anti-depressive effect of CD34 positive stem cell transplantation in rat brain.

在最近的研究中，恢复脑血流成为抑郁症的一种新的治疗策略。为了建立治疗方法研究的动物模型，本课题尝试将CD 34阳性造血干细胞经颈内动脉移植到大鼠脑内，并成功证实其在输注后的大鼠脑毛细血管内增殖。然而，我遗憾地终止了该项目，因为大鼠在输注后1周内的存活率低于60%。

In recent studies, recovery of cerebral blood flow emerged as a novel therapeutic strategy for depression. To establish animal model for the therapy method research, I tried to transplant CD34 positive hematopoietic stem cell into rat brain through the internal carotid artery and succeeded to confirm its proliferation in the rat brain capillaries after transfusion in this project. However, I regretted to discontinue the project because the survival rate of rat was less than 60% within 1 week after transfusion.