Development of contrast-enhanced MR lymphangiography usingclinically available medical agents

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The purpose of this study was to develop novel contrast-enhanced MR lymphangiography methods using clinically available medical agents. First, we employed optical imaging methods to reveal that subcutaneous injection of fluid depicted lymphatic basins in mice, and then MR imaging was conducted with healthy volunteers. After subcutaneous injection of saline (clinically available medical agents) at forearm, lymphatic ducts were clearly depicted on heavy T2 weighted images with post-image processing.