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Polymer gel dosimetry in proton beams

质子束中的聚合物凝胶剂量测定

基本信息

批准号：
22791210
负责人：
KAWAMURA Hiraku
金额：
$ 2.25万
依托单位：
Ibaraki Prefectural University of Health Science
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2010
资助国家：
日本
起止时间：
2010 至 2011
项目状态：
已结题

项目摘要

Polymer gel dosimetry which utilizes chain polymerization that is proportional to radiation dose is a new three-dimensional(3D) dosimetric tool for quality assurance. The purpose of this study was to carry out dosimetry of polymer gels in clinical proton dosimetry. In this study, we caluculated R2 iamges from two and four acquired MR images using an in-house program. We comared the programmed R2 image from two iamges with that from four images. The R2 image from two images was same as that from four images. We can use the R2 image from two images for reduction of scan time. And we performed dose reading method using an X-ray CT scanner for proton beam measurements, in which data collection of thin slices is possible. In addition, we constructed 3D images of polymer gels using volume rendering. As a result, through the collection of thin slices, we could acquire more detailed 3D data. However, we found that at thin slice thicknesses and small voxel, the signal to noise ratio(SNR) around voxels deteriorated.

聚合物凝胶剂量学是一种新型的三维剂量学测量工具，它利用与辐射剂量成正比的链状聚合来保证质量。本研究的目的是开展聚合物凝胶在临床质子剂量测量中的应用。在这项研究中，我们使用内部程序从两个和四个采集的MR图像中计算出R2图像。我们比较了两幅图像和四幅图像的R2图像。来自两个图像的R2图像与来自四个图像的R2图像相同。我们可以使用来自两个图像的R2图像来减少扫描时间。我们使用X射线CT扫描仪进行质子束测量的剂量读数方法，其中可以收集薄片的数据。此外，我们还使用体绘制技术构建了聚合物凝胶的3D图像。因此，通过收集薄片，我们可以获得更详细的3D数据。然而，我们发现在薄层厚度和小体素时，体素周围的信噪比(SNR)恶化。