Development of novel molecular target therapy using high expression protein in prostate cancer

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To development novel molecular target therapy for prostate cancer, we evaluated prostate cancer specificity and tumor growth suppression effect of three candidate protein, which expressed higher in prostate cancer compared with adjacent non-cancerous area. It was suggest that Minichromosome maintenance complex component 5 was the most promising target. Moreover, another novel candidate of peptide vaccine was identified with analysis of mass spectrometry in prostate cancer cell lines. They might be a novel molecular target of prostate cancer.