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3-dimentional lens densitometry measured with Scheimpflug imaging in eyes with cataract

使用 Scheimpflug 成像测量白内障眼的 3 维晶状体密度

基本信息

批准号：
22791683
负责人：
KAWAMORITA Takushi
金额：
$ 2.41万
依托单位：
Kitasato University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2010
资助国家：
日本
起止时间：
2010 至 2011
项目状态：
已结题

项目摘要

The study assessedthe crystalline lens density covering 360 degrees in pupil diameterclose to environment of examination of visual performance and every area using the Scheimpflug densitometry, and to determine their correlation with visual performance.Our results suggest that the quantitation of lens density covering 360 degrees and every area improve predictive accuracyof visual acuity. Also, weconfirmed the effects of refractive index, scatter, and light transmittance on retinal image qualityusing optical simulation software. The 3-D lens densitometry using the Scheimpflug densitometry could be helpful for follow-up of cataractsand quantitation of curative/preventive drug, and could be a potential tool for prediction of visualperformancein cataract patients.

本研究采用Scheimpflug密度计测定视功能检查环境附近瞳孔直径360 °范围内透镜密度及各区域晶状体密度，并探讨其与视功能的相关性，结果表明，对360 °范围内透镜密度及各区域晶状体密度进行定量测定可提高视力预测的准确性。利用光学仿真软件验证了折射率、散射和透光率对视网膜成像质量的影响。采用Scheimpflug密度计的三维透镜密度测量有助于白内障的随访和治疗/预防药物的定量，并可能成为预测白内障患者视觉性能的潜在工具。