Functional analysis of the bone differentiation from isolated mesenchymal stem cell from the apical pulp of human teeth

本研究的目的是分析从人牙髓组织中分离的间充质干细胞（MSCs）的成骨分化功能。在体外培养条件下，成根完全期的成骨功能高于其他各期。从表达成骨功能的CD349标记物中分离的CD349（+）MSCs具有良好的体内成骨分化能力。

The purpose of this study was to analyze the function of the bone differentiation for isolated mesenchymal stem cells (MSCs) from the apical pulp of human teeth. Function of bone differentiation was higher in the stage of completed root formation than other stages in vitro. The CD349 (+) MSCs which were isolated from CD349 marker expressing the function of bone formation were excellent for bone differentiation in vivo.