Availability of measurement of salivary alpha-amylase activity for evaluation of surgical stimuli and postoperative pain
Availability of measurement of salivary alpha-amylase activity for evaluation of surgical stimuli and postoperative pain
批准号:
22792020
负责人:
HIROSE Noriya
金额:
$0.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
在本研究中,在全麻下气管插管和切皮后,唾液α-淀粉酶活性(SAA)显著升高,表明交感神经活动。相反,围手术期和术后的SAA值与SAA、视觉模拟评分(VAS)和术后48小时内止痛药的使用无关。这些结果表明,SAA的测量可能是一种评估全身麻醉下伤害性刺激的方法,然而,评估术后疼痛可能是困难的。
英文摘要
In this study, salivary alpha-amylase activity(sAA) which indicate of sympathetic activity was significantly induced after tracheal intubation and skin incision under general anesthesia. In contrast, perioperative and postoperative sAA values did not associate with sAA, VAS(visual analogue scale) and analgesic agent usage during 48 hours after operation. These results suggest that measurement of sAA might be a method for evaluation of noxious stimuli under general anesthesia, however, it is probably difficult to assess postoperative pain.
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