Evaluation of bioactive peptide kisspeptin as a biomarker

Kispeptin是一种生物活性多肽，已被认为与癌症、性腺功能减退和围产期疾病有关。作者建立了一种灵敏的酶免疫测定法，可以检测血液中Kispeptin的浓度，并试图通过血浆Kispeptin水平作为生物标志物来识别可诊断的疾病。对健康受试者和患者血浆/血清Kispeptin水平的测定和分析表明，血浆Kispeptin水平有望成为围产期并发症的良好生物标志物。

Kisspeptin is a bioactive peptide, which has been suggested to relate with cancers, hypogonadism, and perinatal disease. The author developed a sensitive enzyme immunoassay , which could measure blood kisspeptin concentrations, and tried to we identify diagnosable disease by plasma kisspeptin levels as a biomarker. Measuring and analysis of plasma/serum kisspeptin levels in healthy subjects and patients suggests that plasma kispeptin levels are expected to be a good biomarker for perinatal complication.