Investigation of relationship between gastric carcinogenesis in the young patients and intracellular oxidative stress induced by H. pylori infection

青年胃癌发生与H. pylori感染细胞内氧化应激的关系探讨

• 批准号: 22790345
• 负责人: HエRAHASHエ Minako
• 金额: $ 1.83万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22790345/
• 关键词: 胃癌発癌; H.ピロリ菌; 慢性炎症; 活性酸素; 病理学; 8 hydroxy 2; deoxyguanosne(8OHIG); peroxiredoxin(PRDX); 8-hydroxy-2'-deoxyguanosine (8OHdG); peroxiredoxin (PRDX); 8-hydroxy-2'-deoxyguanosine(80HdG)

Although Helicobacter pylori(H. pylori)-i nfected chronic gastritis is described as accumulating reactive oxygen species(thinthe gastric epithelial cells and as relatingto the carcimgenesis, the further relationshiprenaiins to be conpletely elucidated. Inthis study, ve i nvesti gated the expression of RE relating substances in the gastric cancer and noncancerous gastric nuacosa, and conpared the expressi on i n gastritis, to difference young that patients, under 30 years of age, innot-young pat i ents, nmre than between the two groups. coexisting 40 years of H. age. pyrol 1-i of eat ed W found son

尽管幽门螺杆菌(H。幽门螺杆菌感染的慢性胃炎被描述为活性氧的积累（使胃上皮细胞变薄）并与癌变有关，其进一步的关系尚待完全阐明。本研究研究了胃癌和非癌性胃黏膜中RE相关物质的表达，并比较了其在胃炎中表达的差异，30岁以下的年轻患者和年轻患者之间的差异大于两组之间的差异。共存40岁。pyrol 1-i的儿子发现了他

项目成果

若年者胃癌の特徴中高年に認める胃癌との相違一病理の立場から

青年胃癌特点与中老年人胃癌的区别——从病理角度

• 发表时间: 2011
• 期刊: 胃と腸
• 作者: 平橋美奈子;小田義直
• 通讯作者: 小田義直

EXPRESSI ON OF ANIOXDANT PROIEI NI NTHE INTAAMLOOSAL, POORLY DIFFERENI ATED GASTRIC CANOER NI YOUNG PATI ENTS

抗氧化剂在年轻患者体内、分化差的胃癌中的表达

• 发表时间: 2011
• 作者: 平橋美奈子;小田義直;近藤哲夫;M Hrahashi
• 通讯作者: M Hrahashi

EXPRESSION OF ANTIOXDANT PROTEIN IN THE INTRAMUCOSAL POORLY DIFFERENTIATED GASTRIC CANCER IN YOUNG PATIENTS

抗氧化蛋白在年轻患者黏膜内低分化胃癌中的表达

• 发表时间: 2011
• 作者: 池田博子;他;平橋美奈子
• 通讯作者: 平橋美奈子