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Effects of environmental chemicals on the hematopoiesis of iPS cells

Effects of environmental chemicals on the hematopoiesis of iPS cells
环境化学物质对 iPS 细胞造血的影响
批准号：
22790552
负责人：
ITO Tomohiro
金额：
$2.58万
依托单位：
National Institute for Environmental Studies
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2010
资助国家：
日本
项目状态：
已结题
起止时间：
2010 至 2011
来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22790552/
关键词：
iPS細胞造血幹細胞フタル酸エステルエストロゲン受容体ペルオキシゾーム増殖剤応答性受容体ディーゼル排気微粒子

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中文摘要
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英文摘要
By using iPS cells, effects of phthalate esters on the hematopoiesis were examined. In that system, DEHP suppressed the appearance of hematopoietic progenitor from iPS cells while MEHP, a metabolite of DEHP, accelerated it. It was also suggested that their effects are caused independently of estrogen receptor and peroxisome proliferators-activated receptor.
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    21760307
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