Prognosis and causes of death among patients with childhood-onset type 1 diabetes at the 45-year duration

该研究包括1，385名在1965年至1979年期间被诊断为18岁之前患有1型糖尿病的患者。截至2010年，这一群体的死亡风险比一般人群高10.1倍，男性的风险比女性高1.4倍。然而，30年随访时的死亡风险从1965-69年诊断组的19.0显著改善到1975-79年诊断组的6.9。死亡原因将在死亡率分类委员会讨论后进行分析。

The study comprised 1,385 patients who were diagnosed as having type 1 diabetes before the age of 18 years during 1965 and 1979. The mortality risk of this cohort as of 2010 was 10.1-fold higher than that of the general population, and males had a 1.4-fold higher risk than did females. However, the mortality risk at the 30-year follow-up markedly improved from 19.0 in the 1965-69 diagnosis group to 6.9 in the 1975-79 diagnosis group. The causes of death will be analyzed after a discussion in the mortality classification committee.