The role of Paraoxonase-1 in chronic kidney disease and renovascular injury
The role of Paraoxonase-1 in chronic kidney disease and renovascular injury
批准号:
22790777
负责人:
ICHIKAWA Kazunobu
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
We performed immunohistochemistry for PON1 in rat 5/6 nephrectomy model. It showed that PON1 expression in vascular endothelium was associated with renovascular injury. Then we examined the association of PON1 genotype (rs662) and prognosis among patients with end-stage renal disease. However, there was no significant difference between survival rate and PON1 genotype, suggesting that PON1 gene was not associated with the risk of cardiovascular disease and prognosis in end-stage renal disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
透析患者におけるParaoxonase-1遺伝子多型と生命予後に関する検討
对氧磷酶1基因多态性与透析患者生命预后的研究
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[市川一誠, 今田恒夫, 久保田功, 他]
通讯作者:
他
Polymorphism of proinflammatory cytokine genes and albuminuria in the Japanese general population: the Takahata study
日本普通人群促炎细胞因子基因多态性和蛋白尿:高畑研究
DOI:
10.1093/ndt/gfr105
发表时间:
2011
期刊:
Nephrol Dial Transplant
影响因子:
--
作者:
[Mashima Y, Konta T, Kudo K, Suzuki K, Ikeda A, Ichikawa K, Shibata Y, Watanabe T, Tamiya G, Kato T, Kawata S, Kubota I.]
通讯作者:
Kubota I.
海外基金