Sugar-alcohol for oral mucosal wetness and caries control strategy in compromised child patients

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Oral mucositis is a very frequent and potentially severe complication experienced by patients receiving chemotherapy and/or radiotherapy, which often leads to significant morbidity and mortality, and decreased quality oflife, and is very costly. The condition of dry mouth is also influential in occurrence of caries, periodontal disease and fungal infection. Despite its severity and prevalence, there has been no standard management especially in children. This study evaluated the feasibility of a xylitol spray for the child patients with systemic disease. The results suggest that a xylitol spray is effective on reduction of MS levels in saliva and plaque, and enhancing oral moisture, which leads to improvement of oral conditions.