Molecular biological investigation of periodontal ligament homeostasis in Slc39a13/Zip13 mice

我们的研究目的是探讨Zip13在牙周结石代谢中的作用。为了研究Zip13的生物学作用，我们采用H&E染色、银浸渍、透射电镜（TEM）和免疫染色对由纤维结缔组织和牙周韧带组成的颅脑跟腱和矢状缝合线进行了形态学观察。结果表明Zip13可能在牙周膜稳态中起重要作用。

The aim of our study was to investigate the role of Zip13 in the metabolism of periodontalligament. To examine the biological role of Zip13, we performed the morphologicobservation for Achilles tendon and sagittal suture at the cranium which are comprised of fibrous connective tissue as well as periodontal ligament using H&E staining, silverimpregnation and transmission electron microscope (TEM) and immunostaining. Ourresults reveal Zip13 may play an important role to periodontal ligament homeostasis.