Exercise epidemiological study on therole of serum brain-derived neurotrophic factor as biomarker of depressive symptom and metabolic disorder

本研究的目的是探讨日本工人血清脑源性神经营养因子作为抑郁症状和代谢紊乱的生物标志物的作用。研究对象为350名日本男性工人。研究设计为2年前瞻性研究。因此，在2年的随访中，未观察到血清BDNF浓度与抑郁症状和代谢紊乱的患病率之间存在任何显著相关性

The purpose of present study was to investigate the role of serum brain-derived neurotrophic factor as biomarker of depressive symptom and metabolic disorder in Japanese workers. Subjects were 350 male Japanese workers. Research design was 2 years prospective study. As the result, it is not observed any significant association between serum BDNF concentration and prevalence of depressive symptom and metabolic disorder for 2 years follow-up