Exercise epidemiological study on therole of serum brain-derived neurotrophic factor as biomarker of depressive symptom and metabolic disorder

本研究的目的是探讨血清脑源性神经营养因子作为日本工人抑郁症状和代谢紊乱的生物标志物的作用。受试者为350名日本男性工人。研究设计为2年前瞻性研究。结果发现，在2年的随访期内，血清脑源性神经营养因子水平与抑郁症状和代谢紊乱的患病率之间没有明显的相关性。

The purpose of present study was to investigate the role of serum brain-derived neurotrophic factor as biomarker of depressive symptom and metabolic disorder in Japanese workers. Subjects were 350 male Japanese workers. Research design was 2 years prospective study. As the result, it is not observed any significant association between serum BDNF concentration and prevalence of depressive symptom and metabolic disorder for 2 years follow-up