Challenge for Fabrication of Medical Devices using Next Generation' s Ti Alloy Powders by Laser Forming

使用下一代钛合金粉末激光成型制造医疗器械面临的挑战

• 批准号: 22656169
• 负责人: MIURA Hideshi
• 金额: $ 1.88万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22656169/
• 关键词: 粉末冶金; Ti合金粉末; レーザフォーミング; 医療用デバイス; 粉末積層; 緻密複雑形状

Honeycomb structured compression strength specimens(Ti-6Al-7Nb) which have various honeycomb hole sizes were fabricated in optimizing the process parameters of laser forming. The honeycomb structure with hole diameter of 600μm showed 68-302 MPa in compression strength and 2. 18 g/cm^3 in density. Those values are approximately equal to that of human femur which has 21-170 MPa in compression strength and 2. 00 g/cm^3 in density. In the case of osteobalsts culturing for biocompitability, the cells were oriented in hexagonal shape at the early stage of culturing, and after 21 days the cells growing into the hexagonal shaped holes were observed. In addition, in smaller honeycomb hole size(300μm), network cell growth was formed over the entire area. This means that smaller honeycomb hole size promotes the cell growing into the honeycomb hole, in another word, the laser forming technique might be very reliable to fabricate bio-medical devices.

在优化激光成形工艺参数的基础上，制备了不同尺寸蜂窝孔的Ti-6Al-7 Nb蜂窝结构抗压试件。孔径为600μm的蜂窝状结构的压缩强度为68-302 MPa，2.密度为18 g/cm^3。这些值大致等于人股骨的压缩强度21-170 MPa和2。00 g/cm^3。在为生物相容性培养成骨细胞的情况下，在培养的早期阶段，细胞以六边形形状定向，并且在21天后，观察到细胞生长到六边形形状的孔中。此外，在较小的蜂窝孔径（300μm）下，整个蜂窝区域都形成了网状结构。这意味着较小的蜂窝孔尺寸促进细胞向蜂窝孔中生长，换句话说，激光成形技术可能非常可靠地制造生物医学器件。

项目成果

Laser Forming of Ti-6Al-7Nb Alloy Powder Compacts for Medical Devices

医疗器械用 Ti-6Al-7Nb 合金粉末压块的激光成型

• 发表时间: 2010
• 期刊: Materials Science Forum
• 作者: 津山美穂;他5名;三浦秀士;H. Miura etal 5 people
• 通讯作者: H. Miura etal 5 people

レーザーフォーミング法によるチタン合金部材の高密度・高精度化

采用激光成形方法的高密度、高精度钛合金零件

• 发表时间: 2011
• 作者: H.Miura;et al 5 people;三浦秀士
• 通讯作者: 三浦秀士

金属粉末レーザ積層法によるテーラメイドのTi造形物の実現

使用金属粉末激光沉积方法实现定制钛物体

• 发表时间: 2012
• 期刊: チタンと歯科臨床
• 作者: 津山美穂;他5名;三浦秀士
• 通讯作者: 三浦秀士