Elucidate the pathomechanism of inclusion body myositis(IBM)
Elucidate the pathomechanism of inclusion body myositis(IBM)
批准号:
22659167
负责人:
ITOYAMA Yasuto
金额:
$2.12万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
Sporadic inclusion body myositis(sIBM) is an intractable and progressive skeletal muscle disease of unknown cause and without effective treatment. Our purpose is to elucidate the pathomechanism of sIBM exploring the autoantibody in the serum of sIBM patients using protein array. We also produced muscle specific proteasome deficient mice as the disease model of sIBM.
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Sporadic inclusion body myositis in Japan
日本散发性包涵体肌炎
DOI:
--
发表时间:
2012
期刊:
Nihon Rinsho
影响因子:
--
作者:
[Aoki M, Suzuki N]
通讯作者:
Suzuki N
日本における封入体筋炎の臨床・病理学的特徴の検討
日本包涵体肌炎的临床病理特征检查
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[鈴木直輝, 青木正志…糸山泰人]
通讯作者:
青木正志…糸山泰人
DOI:
10.1212/wnl.0000000000200188
发表时间:
2022-02
期刊:
Neurology
影响因子:
9.9
作者:
[A. Mammen]
通讯作者:
A. Mammen
Prevalence of inclusion body myositis(IBM) in Japanese population
日本人群中包涵体肌炎(IBM)的患病率
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Suzuki N, Aoki M,…Itoyama Y]
通讯作者:
Aoki M,…Itoyama Y
封入体筋炎の病態と頻度
包涵体肌炎的病理学和频率
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[磯部宏, 井上彰, 小林国彦, 前門戸任, 菅原俊一, 大泉聡史, 西條康夫, 弦間昭彦, 森田智視, 萩原弘一, 貫和敏博, 鈴木直輝]
通讯作者:
鈴木直輝
共 6 条
Establishment of a new disease entity as astrocytopathy, and studies on the pathogenesis and treatment for neuromyelitis optica
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批准号:22229008
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$125.3万
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财政年份:2010
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负责人:ITOYAMA Yasuto
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Optic-spinal multiple sclerosis : clarification of pathogenesis, establishment of new disease entity and treatment
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$26.21万
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财政年份:2007
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负责人:ITOYAMA Yasuto
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依托单位:
A Study on the Pathogenesis and Therapy of Optic-Spinal Multiple Sclerosis
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.09万
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财政年份:2005
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负责人:ITOYAMA Yasuto
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依托单位:
COMPARATIVE ANALYSIS OF CLINICAL AND MOLECULAR IMMUNOLOGICAL PATHOGENESES IN SUBTYPES OF MULTIPLE SCLEROSIS IN JAPAN
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批准号:15390271
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.85万
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财政年份:2003
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负责人:ITOYAMA Yasuto
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依托单位:
Comparative analysis of molecular immunopathogenesis in optic-spinal and conventional multiple sclerosis
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批准号:13470131
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.02万
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财政年份:2001
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负责人:ITOYAMA Yasuto
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依托单位:
Mutational analysis in dysferlin gene in patients with muscular dystrophy in Japanese populations.
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批准号:12557058
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.45万
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财政年份:2000
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负责人:ITOYAMA Yasuto
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依托单位:
Genetic analysis in families with amyotrophic lateral sclerosis
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批准号:11470144
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$8.64万
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财政年份:1999
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负责人:ITOYAMA Yasuto
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依托单位:
Clinical epidemiology and analysis of pathomechanisms of optic-spinal form of multiple sclerosis
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批准号:09470150
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.56万
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财政年份:1997
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负责人:ITOYAMA Yasuto
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依托单位:
Molecular genetic study of familial ALS in Japan
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批准号:07457152
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$3.84万
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财政年份:1995
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负责人:ITOYAMA Yasuto
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依托单位:
Study of Immunomechanisms in HTLV-I-Associated Myelopathy(HAM)
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批准号:63480217
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.03万
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财政年份:1988
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负责人:ITOYAMA Yasuto
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依托单位:
Study on demyelinating lesions in human demyelinating disorders
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批准号:60480221
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1985
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负责人:ITOYAMA Yasuto
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依托单位:
海外基金