Identification of alveolar cell induction genes and differentiation of iPS cells into alveolar cells
Identification of alveolar cell induction genes and differentiation of iPS cells into alveolar cells
批准号:
22659160
负责人:
SAIJYO Yasuo
金额:
$1.96万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
In this study, we tried to differentiate mouse iPS cells to alveolar cells in vitro. At first, iPS cells were cultured with ActinA and Wnt3a for 7 days. iPS cells differentiated into endodermal cells expressing Sox17 and Foxa2. iPS cells were further cultured with FGF2 for additional 5 days. Finally, about 8 % iPS cells differentiated into alveolar type II cells determined by SP-C expression and electron microscopy.
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マウス成長肺と傷害修復過程における肺幹細胞の動態解析
小鼠肺生长及损伤修复过程中肺干细胞的动态分析
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ohmori S, Nakamura M, Hino R, Kobayashi M, Tokura Y, 孫若文]
通讯作者:
孫若文
DOI:
10.1038/mt.2010.192
发表时间:
2011-01-01
期刊:
MOLECULAR THERAPY
影响因子:
12.4
作者:
[Katsha, Ahmed M., Ohkouchi, Shinya, Saijo, Yasuo]
通讯作者:
Saijo, Yasuo
マウス成長肺と傷害修復通程における肺幹細胞の動態解析
小鼠肺生长及损伤修复过程中肺干细胞的动态分析
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[孫若文、西條康夫, ら]
通讯作者:
ら
DOI:
10.2119/molmed.2010.00157
发表时间:
2011-07-01
期刊:
MOLECULAR MEDICINE
影响因子:
5.7
作者:
[Suzuki, Kazuhiro, Sun, Ruowen, Saijo, Yasuo]
通讯作者:
Saijo, Yasuo
DOI:
10.1056/nejmoa0909530
发表时间:
2010-06-24
期刊:
NEW ENGLAND JOURNAL OF MEDICINE
影响因子:
158.5
作者:
[Maemondo, Makoto, Inoue, Akira, Nukiwa, Toshihiro]
通讯作者:
Nukiwa, Toshihiro
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