Investigation of a biomarker index on exercise effects with breast cancer survivors who received chemotherapy

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Sedentary behavior is positively associated with an increased risk of obesity and metabolic syndrome. It is suggested that sedentary time has an association with insulin resistance. The breast cancer survivors who received chemotherapy had a tendency towards a sedentary life-style. The purpose of this pilot study was to assess the effect of the amount of time of physical activity intensity levels on insulin resistance, weight gain and body composition among breast cancer survivors who received chemotherapy. Insulin resistance was measured through the Homeostasis Model Assessment score (HOMA-R). The rate of weight gain was strongly negatively correlated with the average amount of time with more than 3.0 METs (metabolic equivalent). We are continuing to collect data to increase the sample size.