Clarification of autonomic functions of fetuses over time from the late stage of pregnancy to the intrapartum period by heart rate variability analysis

通过心率变异性分析阐明胎儿从妊娠后期到产时随时间变化的自主神经功能

• 批准号: 22659419
• 负责人: NAKAGAKI Akemi
• 金额: $ 2.37万
• 依托单位: Aichi Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659419/
• 关键词: 心拍変動; 自律神経機能; 胎児; 新生児; 妊産婦; 妊婦; 周波数解析; 超音波

A method for detecting a peak corresponding to an electrocardiographic R wave from Doppler heart rate signals was devised to clarify autonomic functions of fetuses during pregnancy and the intrapartum period. In order to verify the validity of this detection method, evaluation of heart rate signals and electrocardiography was conducted simultaneously in adults and newborns and the correlation of these data was examined. The results indicated that these data had a high correlation and could be used for the study. Measurements were conducted on pregnant women to examine the autonomic functions of fetuses and the synchronism between mothers and fetuses. In order to develop this study in the future, the adequateness of the peaks detected in fetuses will be verified by using echographic images, etc.

为了明确胎儿在妊娠期和分娩期的自主神经功能，设计了一种从多普勒心率信号中检测与心电图R波相对应的峰值的方法。为了验证该检测方法的有效性，同时对成人和新生儿的心率信号和心电图进行评估，并检查这些数据的相关性。结果表明，这些数据具有较高的相关性，可以用于研究。对孕妇进行了测量，以检查胎儿的自主神经功能和母亲与胎儿之间的同步性。为了今后开展这项研究，将通过使用回波描记图像等来验证在胎儿中检测到的峰值的适当性。