Visualization of nanomaterials and immune responses to them in infection barrier-tissue

为了可视化组织中纳米材料和免疫反应的动态，我们开发了以下两种技术。1.除了纳米材料的三维运动外，它们的旋转运动对于揭示它们在组织中的动力学也是至关重要的。因此，我们合成了极化半导体纳米晶体，并证明了纳米材料的旋转单粒子跟踪。2.半导体纳米晶在特定条件下诱导细胞凋亡。此外，我们证实巨噬细胞吞噬凋亡细胞。

To visualize the dynamics of nanomaterials and immune responses in tissue, we have developed two techniques described below. 1. In addition to three dimensional motion of nanomaterials, their rotational motion is also crucial to reveal their dynamics in tissue. Thus, we synthesized polarized-semiconductor nanocrystals and demonstrated rotational single particle tracking of the nanomaterial. 2. Semiconductor nanocristals induced apoptosis in a specific condition. Furthermore, we confirmed that macrophages phagocyte the apoptotic cells.