Development of new type of temperature-responsive cell culture surfaces with stretchable properties

点击翻译按钮获取中文摘要

A method of mechanical-assisted control of the polymer thickness and density of temperature-responsive cell culture surfaces was developed by grafting PIPAAm onto PDMS surfaces. Hydrophobicity of the PIPAAm-PDMS surfaces was readily controlled by stretching the surfaces. Further investigation of PIPAAm-PDMS surfaces demonstrated that this hydrophobicity control is because the polymer thickness and density is altered by the stretching. This result suggests that such control may attain producing cell adhesive surfaces appropriate for variety of target cells by stretching one PIPAAm-PDMS surfaces.