The effect on vascular endothelial function by physical stimuli and the differences in the influence by lifestyle

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The purpose of this study was to determine whether thermal or cold stimuli for peripheral vessel have an influence on endothelium function. The participants were 30 healthy men(20-21 years old, smoker 15 men and non-smoker 15 men). The smoking group and non-smoking group were compared, and RHI values of baseline, after thermal stimulus, and after cold stimulus in each group were compared. Significant difference was observed between smoking and non-smoking group with RHI(p<0.01). There was no significant difference in the comparison of RHI between baseline, after thermal stimulus, and after cold stimulus. This suggests that even if younger and short smoking duration, the chemical damage by smoking exert influence on vascular dilatation function derived from vascular endothelium.