Clarify the mechanism of attenuating effect at muscle fatigue by carnosine ingestion.

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In recent year, Carnosine attract at home and abroad attention as supplement with potential attenuating effect at muscle fatigue. The purpose of this study was clarified the mechanism of attenuating effect at muscle fatigue by carnosine ingestion, in particular, sarcoplasmic reticulum(SR) function that occur with high-intensity exercise and muscle energy metabolism during isometric knee extension exercise. In the results, attenuating effect at muscle fatigue by carnosine ingestion were participate in improvement of SR function and inhibiting the degradation of intracellular pH.