Study on the effect of X-irradiation to mammalian preimplantation embryo

X射线照射对哺乳动物着床前胚胎影响的研究

• 批准号: 22710058
• 负责人: YOSHIDA Shuhei
• 金额: $ 2.58万
• 依托单位: Osaka City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22710058/
• 关键词: 生物影響; 環境; 放射線; 受精卵

It is important to analyze the effect of X-irradiation to mammalian fertilized eggs for people hoping childbirth. We found that in X-irradiated mouse preimplantation embryo, cell division was delayed, hatching rate was decreased, Apoptosis was induced, and DNA repair factors were assembled at double strand breaks by X-irradiation.

对于希望分娩的人来说，分析 X 射线照射对哺乳动物受精卵的影响非常重要。我们发现，在X射线照射的小鼠植入前胚胎中，细胞分裂被延迟，孵化率降低，细胞凋亡被诱导，并且DNA修复因子在X射线照射的双链断裂处组装。