Screening of house dust mite allergy vaccine candidates using full-length cDNA library.
Screening of house dust mite allergy vaccine candidates using full-length cDNA library.
批准号:
22710202
负责人:
NIHEI Akiko
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
This study aims at establishing the basis for development of a vaccine for allergy caused by house dust mites(HDM). Expression vectors were constructed using 20 identified and 20 unknown genes selected from about 10, 000 clones in a full-length cDNA library of HDM. These vectors and empty vectors were then administered to different groups of mice, followed by provocation with HDM. The development of HDM-induced allergic diseases was comparable between the two mouse groups, indicating that the pre-treatment with the products of the selected 40 genes was not effective as a vaccine for HDM-mediated allergy.
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DOI:
10.4049/jimmunol.1004054
发表时间:
2011-05-01
期刊:
JOURNAL OF IMMUNOLOGY
影响因子:
4.4
作者:
[Suzukawa, Maho, Nagase, Hiroyuki, Ohta, Ken]
通讯作者:
Ohta, Ken
cetylglucosaminyltransferase V-deficiency increases susceptibility to murine mala
十六烷基葡萄糖胺转移酶 V 缺乏会增加对小鼠疟疾的易感性
DOI:
10.1016/j.exppara.2011.07.003
发表时间:
2011
期刊:
Experimental Parasitology
影响因子:
2.1
作者:
[Nishimoto N, Takagi N., Akiko Shibui]
通讯作者:
Akiko Shibui
気道炎症におけるMgat5の役割
Mgat5 在气道炎症中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Akiko Shibui, Aya Nambu, Eri Shimura, Sachiko Yamaguchi, Chiharu Shiraishi, Yoshitaka Sato, Ko Okumura, Sumio Sugano, Nobumichi Hozumi, Susumu Nakae, 吉村文彦,谷野圭持, Akiko Shibui, Akiko Shibui, Akiko Shibui, Maho Suzukawa, 渋井秋子]
通讯作者:
渋井秋子
N-acetylglucosaminyltransferase V-deficiency increases susceptibility to murine malaria.
N-乙酰氨基葡萄糖转移酶 V 缺乏会增加对鼠疟疾的易感性。
DOI:
--
发表时间:
2011
期刊:
Experimental parasitology
影响因子:
2.1
作者:
[A. Shibui, J. Doi, M. Tolba, C. Shiraishi, Yoshitaka Sato, S. Ishikawa, J. Watanabe, S. Nogami, S. Nakae, S. Sugano, N. Hozumi]
通讯作者:
N. Hozumi
DOI:
10.1016/j.cyto.2012.03.018
发表时间:
2012-07
期刊:
CYTOKINE
影响因子:
3.8
作者:
[Shibui, Akiko, Shimura, Eri, Nambu, Aya, Yamaguchi, Sachiko, Leonard, Warren J., Okumura, Ko, Sugano, Sumio, Sudo, Katsuko, Nakae, Susumu]
通讯作者:
Nakae, Susumu
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A Study of The farm village woman's career formation s
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批准号:16580192
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.9万
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财政年份:2004
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负责人:NIHEI Akiko
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依托单位:
海外基金