Carbohydrate recognition mechanisms of galectins and carbohydrate processing enzymes deduced from X-ray structures
Carbohydrate recognition mechanisms of galectins and carbohydrate processing enzymes deduced from X-ray structures
批准号:
23370054
负责人:
KAMITORI Shigehiro
金额:
$12.65万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-01 至 2014-03-31
中文摘要
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英文摘要
Cell surface oligosaccharides are involved in immune responses and bacterial/viral infections, and they are specifically recognized by carbohydrate-binding proteins. X-ray structures of the complexes of carbohydrate-binding proteins with the target oligosaccharides have been determined to elucidate the carbohydrate recognition mechanisms. The results of this research project give new insights into the carbohydrate recognition mechanisms of galectin-8, a hemagglutinin subcomponent of the botulinum neurotoxin, and an endolysin encoded by episomal phage of Clostridium perfringens.
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DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[神澤範行, 村上良子, 前田裕輔, 木下タロウ, 山下哲]
通讯作者:
山下哲
Crystal structures of rare disaccharides, α-D-glucopyranosyl β-D-psicofuranoside, and α-D-galactopyranosyl β-D-psicofuranoside
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DOI:
10.1016/j.carres.2011.04.003
发表时间:
2011
期刊:
Carbohydr Res
影响因子:
--
作者:
[Shigehiro Kamitori, et al]
通讯作者:
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人半乳糖凝集素9突变体的X射线结构和碳水化合物亲和力分析
DOI:
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发表时间:
2013
期刊:
影响因子:
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作者:
[寺岡美沙, 吉田裕美, 西望, 中北愼一, 神鳥成弘]
通讯作者:
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DOI:
--
发表时间:
2013
期刊:
影响因子:
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作者:
[Yoshida, H., Nishi, N., Teraoka, M., Yamashita, S & Kamitori, S]
通讯作者:
S
ウエルシュ菌特異的溶菌酵素Psmの酵素活性中心の解析
产气荚膜梭菌特异性裂解酶Psm的酶活性中心分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[大保 貴嗣, 山崎 和生, Danko Stefania, 鈴木 裕, 玉井栄治]
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共 22 条
Signaling-molecular mechanism of a novel microglia EF-hand protein Iba1 deduced from X-ray structures
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批准号:20570109
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
-
财政年份:2008
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负责人:KAMITORI Shigehiro
-
依托单位:
Structural study of the microglia/macrophage-specific protein Iba1 from human and mouse having an actin-binding activity
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批准号:18570109
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.49万
-
财政年份:2006
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负责人:KAMITORI Shigehiro
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依托单位:
Study of the cyclodextrin hydrolyzing mechanism of Thermoactinomyces vulgaris R47 α-amylases based on X-ray structures
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批准号:14580621
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2002
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负责人:KAMITORI Shigehiro
-
依托单位:
Study on Substrates-Recognition Mechanism of Thermoactinomyces vulgaris R-47 α-Amylase 2 (TVAII) based on X-ray Structures.
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批准号:12680606
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
-
财政年份:2000
-
负责人:KAMITORI Shigehiro
-
依托单位:
海外基金