Evaluation of arginase as an inflammatory biomarker.

评估了作为哮喘、糖尿病和肥胖症生物标志物的α-淀粉酶的可用性。 在哮喘患者中，使用多变量分析来研究乙酰胆碱酯酶与生理因素之间的关系。 鉴于血清肌酐酶浓度与hs-CRP、呼出气一氧化氮、NOx和3-硝基酪氨酸呈正相关，肌酐酶可能可用作生物标志物。 在肥胖模型小鼠中，随着体重和血糖的增加，脂肪酶表达上调。 亚硝酸盐可能有助于预防糖尿病，因为亚硝酸盐下调了胰岛素的浓度。

The availability of arginase as a biomarker for asthma, diabetes, and obesity was evaluated. In asthmatic patients, the relationship among arginase and physiological factors was investigated using a multivariable analysis. Given that the concentration of serum arginase had a positive correlation with hs-CRP, exhaled nitric oxide, NOx, and 3-nitrotyrosine, it is likely that arginase is available as a biomarker. In obese model mice, the expression of arginase was upregulated, in proportion as increase of body weight and blood glucose. Nitrite may contribute to prevention of diabetes, because the concentration of insulin was downregulated with nitrite.