Molecular analysis of inflammasome in periodontal tissue destruction and regeneration.
Molecular analysis of inflammasome in periodontal tissue destruction and regeneration.
批准号:
23390478
负责人:
YAMADA SATORU
金额:
$12.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-01 至 2014-03-31
中文摘要
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英文摘要
In this study, we investigated expression pattern of inflammasome in periodontal tissue and cells to assess the involvement of inflammasome in periodontal tissue homeostasis, destruction and regeneration. It was shown that inflammasome-associated molecules are expressed in periodontal tissues and cells in normal conditions and these expressions are up-regulated in inflammatory conditions. Periodontal ligament associated extracellular matrix (PDL-ECM) proteins show the interaction with inflammasome, suggesting the regulation of tissue-homeostasis and inflammatory responses by PDL-ECM-inflammasome pathway.
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歯根膜特異的PLAP-1によるFGF-2機能の制御
牙周膜特异性 PLAP-1 对 FGF-2 功能的调节
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[粟田敏仁, 山田 聡, 山羽聡子, 阪下裕美, 津島賢一朗, 梶川哲宏, 北村正博, 村上伸也]
通讯作者:
村上伸也
網羅的遺伝子解析が担う歯周病研究の未来-歯根膜特異的分子PLAP-1遺伝子多型が歯根膜機能へ及ぼす影響-
基于综合遗传分析的牙周病研究未来 - 牙周膜特异性分子PLAP-1基因多态性对牙周膜功能的影响 -
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Tomoko Majima, Ikuyo Nagasaka, Mika Kozu, Mariko Masujima, Akemi Okamoto, Miwa Watanabe, Junko Kusunoki, 山田聡]
通讯作者:
山田聡
Anti-inflammatory Function of PLAP-1 in Periodontal Ligament Cells
PLAP-1在牙周膜细胞中的抗炎功能
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Yamaba S, Yamada S, Kajikawa T, Ozaki N, Awata T, Sakashita H, Yanagita M, Kitamura M, Murakami S]
通讯作者:
Murakami S
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Yamaba S, Yamada S, Kajikawa T, Ozaki N, Awata H, Sakashita H, Yanagita M, Kitamura M, Murakami S]
通讯作者:
Murakami S
Molecular basis of periodontal ligament: Identification and characterization of periodontal ligament specific molecule, PLAP-1
牙周膜的分子基础:牙周膜特异性分子PLAP-1的鉴定和表征
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[T Ooka, Y Inoue, S Hironaka, Y Mukai, Satoru Yamada]
通讯作者:
Satoru Yamada
共 17 条
Retrospective quantitative analysis of juvenile stress using dentin matrix
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批准号:20K21668
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.08万
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财政年份:2020
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负责人:YAMADA SATORU
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依托单位:
Feasible study for developing novel periodontal tissue regeneration therapies by chemical biological approaches
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批准号:26670893
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2014
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负责人:YAMADA SATORU
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依托单位:
Molecular pathogenesis of aggressive periodontitis utilizing hereditary connective tissue disorder mouse model
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批准号:24659923
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2012
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负责人:YAMADA SATORU
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依托单位:
海外基金