Recovery and improvemant of muscle functions by bathing with artificially made high concentration CO2 water

当我们在富含二氧化碳（超过1000 ppm）的温泉中洗澡时，皮肤血管在35摄氏度左右的水温下扩张，皮肤血流增加。动物实验表明，前列腺素E2（PGE 2）参与了这种血管扩张。相反，PGE 1、PGI 2和一氧化氮可能对血管舒张没有贡献。这些PG的生物合成的最后一步的酶的表达没有改变，在CO2-水浴30分钟。结果表明，洗澡与CO2-水可能会影响的量，但在皮肤中的酶的活性。另一方面，水下部分骨骼肌血管扩张，血流量增加。抗阻运动后肌肉酸痛和硬度的恢复，用CO2-水洗澡比用普通水更快。结果提示，CO_2水浴可改善肌功能。

Skin blood vessel is dilated at the water temperature of around 35 degrees Celsius when we take a bath in carbon dioxide-rich (more than 1000ppm) hot-spring, and skin blood-flow increases. Animal experiments revealed that prostaglandin E2 (PGE2) is involved in this vasodilatation. In contrast, PGE1, PGI2 nor nitric oxide may not contribute to the vasodilation. Expression of enzymes contributing to the final step of the biosynthesis of those PGs was not changed during CO2-water bathing for 30 min. The results suggest that bathing with CO2-water may affect not the amount but the activity of the enzyme in the skin. On the other hand, the blood vessels in skeletal muscle of underwater body part was dilated, which produced increase of blood flow. Muscle soreness and hardness after resistance exercise was recovered by bathing with CO2-water more quickly than that with normal water. The result suggest that the CO2-water bath may improve a myofunction.