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Therapeutic effect of repetitive transcranial magnetic stimulation in chronic aphasia patients and brain activation patterns

Therapeutic effect of repetitive transcranial magnetic stimulation in chronic aphasia patients and brain activation patterns
重复经颅磁刺激对慢性失语症患者的治疗效果及脑激活模式
批准号:
23500633
负责人:
OKAZAKI Tetsuya
金额:
$3.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
翻译
我们对慢性失语症患者每天对右脑Broca‘s同源物进行抑制性重复经颅磁刺激(RTMS),连续10天。虽然失语症在描述性观察中得到了改善,但标准语言测试显示rTMS治疗后没有明显改善,近红外光谱图获得的偏侧性指数显示,大多数患者在图片命名任务中表现出右侧优势脑激活。RTMS治疗前后偏侧指数变化趋势不一致。
英文摘要
We applied inhibitory repetitive transcranial magnetic stimulation (rTMS) to right-hemisphere Broca's homologue daily, for 10 days in chronic aphasia patients. Although improvement of aphasia was admitted in a descriptive observation, standard language test showed no significant improvement after rTMS treatments, Laterality index, which obtained by near-infrared spectroscopic mapping, revealed most patients demonstrate right dominance brain activation during picture naming task. Then, change in laterality index before and after rTMS treatments did not show uniform trend.
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