Control of Formose Reaction Using Polymer Nanostructures

为了构建选择性地产生特定目标产物的甲醛糖反应体系，本文对气溶胶OT（AOT）反胶团和含硼酸残基聚合物的甲醛糖反应进行了详细的研究。 AOT反胶团的甲醛糖反应具有很高的选择性，优先生成2个碳原子的甲醛糖，而3个或3个以上碳原子的糖没有明显生成。 与低分子量硼酸和具有硼酸残基的聚合物的甲醛反应也表明甲醛的选择性形成，这取决于硼酸物质的类型。 此外，还合成了一些新的聚合物作为甲醛反应的反应介质。

Aiming at construction of formose reaction systems which selectively yield specific saccharides, formose reaction using aerosol OT (AOT) reverse micelles and polymers possessing boronic acid residues have been investigated in detail. The formose reaction with AOT reverse micelles exhibit rather high selectivity, in which formoses of two carbon atoms were formed preferentially whereas sugars of three or more carbon atoms were not produced significantly. The formose reaction with a low molecular weight boronic acid and polymers possessing boronic acid residues also indicated selective formation of formoses, depending on the type of boronic acid species. Furthermore, some new polymers were synthesized as reaction media for formose reaction.