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Clarified the active mechanisms of the multiple functions of mushrooms within the human body after consumption

Clarified the active mechanisms of the multiple functions of mushrooms within the human body after consumption
阐明食用菌多种功能在人体内的激活机制
批准号:
23580234
负责人:
EGUCHI FUMIO
金额:
$3.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
It has been shown that mushroom basidiocarp hot water extract suppresses platelet aggregation. Platelet aggrgation is caused by platelets binding to PAF receptors. The platelet aggregation suppression effect of many mushrooms not only promotes TXA2 through COX metabolism, both PLA2 and activity in the domain of regeneration of 1-alkyl phosphatidycholine, a cell membrane phospholipid, have also been confirmed. Also, suppression of ADP's production, which stems from the process passing from breakdown of vascular endothelials to dense granule platelet production, has been shown. Because mushroom are an active material in a wide range of platelet aggregation suppressive functions, regularly eating mushrooms is now known to contribute to improving the symptoms of vascular endothelial diseases by stimulating the blood vessels, neutrophil activation, and smooth muscle contraction, improving renal hypertension, and aiding other functions related to platelet aggregation.
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DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [茂木園美, 吉本博明, 菊川忠裕, 江口文陽]
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作者: [西島純基, 鷲見亮, 森伸夫, 江口文陽]
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DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [木田マリ, 宮澤紀子, 吉本博明, 江口文陽]
通讯作者: 江口文陽
DOI: --
发表时间: 2011
期刊: Mushroom Science and Biotechnology 19(1)
影响因子: --
作者: [Fumio EGUCHI, Noriko MIYAZAWA, Takahide MATSUDA]
通讯作者: Takahide MATSUDA
20
    Elucidation of the multifunctional expression of mushrooms based on inflammatory regenerative medicine and neuroscience
    • 批准号:
      20H03050
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.23万
    • 财政年份:
      2020
    • 负责人:
      EGUCHI FUMIO
    • 依托单位:
    The development of cultivation technology of highly advanced functional mushroom for age-related diseases and the evaluation of its efficacy
    • 批准号:
      26450235
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.24万
    • 财政年份:
      2014
    • 负责人:
      EGUCHI FUMIO
    • 依托单位:
    海外基金