Characterization of a novel lipoprotein receptor (LRP12) in chicken liver –The basic knowledge for lipid metabolism -
Characterization of a novel lipoprotein receptor (LRP12) in chicken liver –The basic knowledge for lipid metabolism -
鸡肝中新型脂蛋白受体（LRP12）的表征-脂质代谢的基础知识-
批准号：
23580385
负责人：
KAN Sato
金额：
$3.41万
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2011
资助国家：
日本
项目状态：
已结题
起止时间：
2011 至 2013
中文摘要
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英文摘要
In present study, the function of LDL receptor related protein 12 (LRP12), a novel lipoprotein receptor in chickens, was characterized, and it is possible to utilize as the improvement in efficiency of the egg and meat production in chickens. LRP12 gene expression was high in liver of laying hens. Chicken LRP12 is the molecule for the uptake of LDL into cells, and it is a master regulator of lipoprotein uptake in chicken liver. In addition, LRP12 is characterized that the gene expression and lipoprotein uptake were no changed by the intracellular cholesterol concentrations of cells, and it plays the important role for the lipid recycling of liver-blood lipid-liver in chickens.
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会议论文
DOI：
10.1016/j.ygcen.2011.11.043
发表时间：
2012-02-01
期刊：
GENERAL AND COMPARATIVE ENDOCRINOLOGY
影响因子：
2.7
作者：
[Sato, Kan, Aoki, Michiru, Kamada, Tosihiko]
通讯作者：
Kamada, Tosihiko
dministration of insulin to newly hatched chicks improves growth performance via impairment of MyoD gene expression and enhancement of cell proliferation in chicken myoblasts.
对新孵出的雏鸡施用胰岛素可通过损害 MyoD 基因表达并增强鸡成肌细胞的细胞增殖来改善生长性能。
对新孵出的雏鸡施用胰岛素可通过损害 MyoD 基因表达并增强鸡成肌细胞的细胞增殖来改善生长性能。
DOI：
--
发表时间：
2012
期刊：
Gen Comp Endocrinol.
影响因子：
--
作者：
[Sato, K., Aoki, M., Kondo, R., Matsushita, K., Akiba, Y., Kamada, T.]
通讯作者：
T.
DOI：
10.1016/j.cbpa.2010.10.028
发表时间：
2011-02-01
期刊：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
影响因子：
2.3
作者：
[Sato, Kan, Kamada, Toshihiko]
通讯作者：
Kamada, Toshihiko
海外基金
