课题基金 / 基金详情

Epidemiology in patients with COPD with depression and sleep disorder and systemic biomakers in depressed COPD patients in Japan

Epidemiology in patients with COPD with depression and sleep disorder and systemic biomakers in depressed COPD patients in Japan
日本患有抑郁症和睡眠障碍的慢性阻塞性肺病患者的流行病学以及抑郁型慢性阻塞性肺病患者的全身生物标志物
批准号:
23591130
负责人:
KAWAYAMA Tomotaka
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

项目摘要

项目成果

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The prevalence of depression and sleep disorder in patients with COPD was significantly higher than in the controls, and the relative risk of depression and sleep disorder in COPD was 7.6 and 1.8-folds, respectively. The COPD patients with depression had significantly more frequent exacerbations and hospitalizations than those without depression or sleep disorder.The plasma 5-hydroxyindole acetic acid (5-HIAA), metabolite of serotonin, level in depressed COPD patients was significantly higher than in non-depressed COPD patients and non-smokers, but not smokers. The plasma 5-HIAA level was significantly associated with the severity of depression in patients with COPD.The management for depression and sleep disorder is necessary in patients with COPD, and the measurement of plasma 5-HIAA levels may be helpful to detect the depression in patients with COPD.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1016/j.resinv.2012.05.003
发表时间: 2012-06-01
期刊: RESPIRATORY INVESTIGATION
影响因子: 3.1
作者: [Tsuda, Tohru, Suematsu, Rika, Aizawa, Hisamichi]
通讯作者: Aizawa, Hisamichi
特集ガイドラインをふまえ、気管支喘息の病態研究・治療の最前線に迫る「心不全合併喘息の臨床対応はどのようにおこなうか」
基于专题指南,我们走近支气管哮喘病理研究和治疗的最前沿,“临床上该如何应对哮喘并发心力衰竭?”
DOI: --
发表时间: 2013
期刊: Respiratory Medical Research
影响因子: --
作者: [川山智隆, 木下隆, 一木裕子, 松永和子, 星野友昭]
通讯作者: 星野友昭
Safety and efficacy of NVA237 once daily in Japanese patients : the GLOW4 trial
NVA237 每天一次在日本患者中的安全性和有效性:GLOW4 试验
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Sekiya M, Kawayama T, Fukuchi Y, Takahashi T, Kaiso T, Ikeda K, Overend T, Banerji D]
通讯作者: Banerji D
COPDの気道炎症とその制御
COPD 中的气道炎症及其控制
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Koichiro Nozaki, Hiroshi Kagamu, Jun Koshio, Kosuke Ichikawa, Yu Saida, Tomohiro Tanaka, Satoshi Watanabe, Hirohisa Yoshizawa, and Ichiei Narita, 川山智隆]
通讯作者: 川山智隆
44
    海外基金