The combination therapy of the cancer-vaccine therapy and the preoperative chemoradiotherapy for rectal cancer (phase I trial)

直肠癌癌症疫苗治疗与术前放化疗联合治疗（I期试验）

• 批准号: 23591954
• 负责人: TSURITA Giichiro
• 金额: $ 3.41万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23591954/
• 关键词: 直腸癌; 術前放射線化学療法; 癌ペプチド; 腫瘍特異的ワクチン療法; 臨床試験; 免疫療法

This study was a phase I clinical trial of the therapy, combined preoperative chemoradiotherapy with tumor-specific vaccine therapy, for the cases with advanced rectal cancer. The purpose of this study was to examine the safety of this combination therapy. Unfortunately, this clinical trial, however the protocol of this clinical trial or the document of informed consent was prepared in the first year, was not able to be performed within research periods.It was useful, however, in performing this clinical trial in future, to analyze the data of the advanced rectal cancer cases performed preoperative chemoradiotherapy, or to locate and educate not only medical doctors but also nurses, pharmacists, and medical technicians for this study.

本研究为术前放化疗联合肿瘤特异性疫苗治疗晚期直肠癌的I期临床试验。本研究的目的是检查这种联合治疗的安全性。遗憾的是，尽管该临床试验的方案或知情同意书是在第一年准备的，但该临床试验未能在研究期间内进行。然而，在将来进行该临床试验时，分析进行术前放化疗的晚期直肠癌病例的数据，或不仅找到并教育医生，而且还找到护士，药剂师，和医疗技术人员进行这项研究。