Study of myocardial protection by sympathetic nerve stimulation using a new SPY-Q system myocardial blood flow evaluation

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The purpose of this study is to obtain safety cardiac arrest by sustained stimulation of bilateral sympathetic nerve and Ganglion Plexus. Using a pen type bipolar stimulation device (25-30 Hz, rectangular bipolar pulse, output 8 V, pulse width 0.4 ms) with distance between electrodes 3 mm, a stable cardiac arrest was obtained during 30 minutes. During stimulation (30 minutes), cardiac arrest was obtained and after stopping stimulation, heart beating was started immediately. Heart rate and systemic blood pressure were recovered to the controlled value in about 10 minutes. During cardiac arrest, myocardial blood flow and myocardial oxygen saturation were not decreased. The new cardiac protection of the sympathetic nerve stimulation resulted in safe and useful methods without decreasing of cardiac dysfunction and myocardial oxygen metabolism.