Development of Catheter therapy for ventricular sqptal perforation

我们开发了一种通过在左心室放置支架移植物来治疗室间隔穿孔(VSP)的导管疗法。我们采用网状支架，由尼提诺线编织而成。作为最初的模型，我们制作了锥形支架移植物，但它不适合乳头肌。我们改变了支架移植物的设计，使之具有不对称性。改进后的模型仅覆盖隔膜，但隔侧特别是隔基底侧的压力功率较弱。我们制作了经根尖直接插入的输液鞘，并利用PEAL Off系统开发了一种插入方法。我们使用该输送系统将支架移植物植入橡胶心脏模型。支架移植物可以通过左心室心尖部插入，并将其作为设计，通过将其固定在心尖部来保持方向性。不影响心脏功能的支架移植物的设计决定是困难的，目前仍处于试验完成阶段。

We developed a catheter therapy for ventricular septum perforation (VSP) by using a stent-graft placed in the left ventricle. we adapt a net type stent which is knitted by a Nytinol thread. As an initial model, we made a cone-shaped stent-graft but it did not fit with papillary muscles. We changed the design of the stent-graft as a dissymmetry. It covered only with the septum but a pressure power of the septum side particularly the septum base side was weak even with the improved model.We made delivery sheath for direct insertion via the apex and developed an insertion method by using peal off system. We insert a stent-graft into a rubber heart model by using this delivery system. The stent graft can be inserted via the left ventricle apex and has it as a design preserving the directionality by fixing it in the apex. The design decision of the stent-graft which does not affect cardiac function is difficult and remains in the completion of a trial