Endoplasmic reticulum stress response in motor neuron after transient ischemia in rabbits

本研究的目的是探讨内质网应激反应在家兔短暂性脑缺血后运动神经元死亡中的作用。然而，不可能提取足够用于分析的内质网应激相关蛋白。因此，我们研究了自噬介导的应激反应的作用。我们认识到，自噬诱导的延长可能是一个潜在的因素，负责延迟运动神经元死亡，自噬抑制蛋白Bcl-2的诱导。

The purpose of the present study was to investigate the role of endoplasmic reticulum stress response in motor neuron death after transient ischemia in rabbits. However it was not possible to extract the edoplasmnic reticulum stress relation protein enough for the analysis. Therefore, we investigated the role of autophagy-mediated stress response. We recognized that the prolonged induction of autophagy might be a potential factor responsible for delayed motor neuron death, and the induction of the autophagy inhibitory protein Bcl-2.