Osteoconductive effect of spatial design and thermal oxidation on Pure Ti and Ti-15Zr-4Ta-4Nb alloy

空间设计和热氧化对纯钛和Ti-15Zr-4Ta-4Nb合金的骨传导作用

• 批准号: 23592190
• 负责人: MASHIMA Naohiko
• 金额: $ 3.33万
• 依托单位: Ehime University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592190/
• 关键词: 人工関節; チタン合金; 骨芽細胞; 力学試験; 骨伝導; 生体材料金属; Bioactive

Apatite formation on the surface of titanium and its alloys is effective for inducing osteoconductivity when implanted in bony defects . One of these approaches is "GRAPE Technology," by which titanium and its alloys is grooved and thermally treated. The aim of this study was to investigate the osteoconductive effects of this technology when implanted using bone grafting in bony defects. Using Ti-15Zr-4Nb-4Ta alloy processed by this technique, we assessed the growth morphology, proliferative capacity, and differentiation activity of osteoblasts on the alloy. It was suggested that Ti-15Zr-4Nb-4Ta alloy processed employing GRAPE Technology, might enhance the growth rate and differentiation of osteoblasts to achieve favorable bone fixation .

当植入骨缺损时，钛及其合金表面的磷灰石形成可有效诱导骨传导性。其中一种方法是“GRAPE技术”，通过该技术对钛及其合金进行开槽和热处理。本研究的目的是研究在骨缺损中使用植骨植入时该技术的骨传导效应。采用该技术处理的Ti-15 Zr-4 Nb-4 Ta合金，我们评估了成骨细胞在该合金上的生长形态、增殖能力和分化活性。结果表明，采用GRAPE技术处理的Ti-15 Zr-4 Nb-4 Ta合金可提高成骨细胞的生长速度和分化，从而实现良好的骨固定。

项目成果

Ti-Mo合金のα″相およびathermalω相生成に及ぼすFe添加効果

Fe添加对Ti-Mo合金中α″相和无热ω相形成的影响

• 发表时间: 2013
• 作者: 8.Koto K;Murata H;Kimura S;Sawai Y;Horie N;Matsui T;Ryu K;Ashihara E;Maekawa T;Kubo T;Fushiki S.;宮本晃,小林千悟,岡野聡,仲井清眞,阪本辰顕
• 通讯作者: 宮本晃,小林千悟,岡野聡,仲井清眞,阪本辰顕

Effect of hot-wire on microstructure and mechanical property in weld metal formed with CO2 gas shielded arc welding method

热丝对CO2气体保护焊焊缝金属显微组织和力学性能的影响

• 发表时间: 2013
• 期刊: Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society
• 作者: Tsuyama;T.;Nakai;K.;Noumaru;K.;Sakamoto;T.;Kobayashi;S
• 通讯作者: S

Clinical and radiographic evaluation of total hip arthroplasties using porous tantalum modular acetabular components: 5-year follow-up of clinical trial

• DOI: 10.1007/s10165-012-0618-9
• 发表时间: 2013-01-01
• 期刊: MODERN RHEUMATOLOGY
• 影响因子: 2.2
• 作者: Nakashima, Yasuharu;Mashima, Naohiko;Iwamoto, Yukihide
• 通讯作者: Iwamoto, Yukihide

Effects of microstructure on mechanical property in weld metal formed with the hot-wire method applying ordinal CO2 gas shielded arc welding method

普通CO2气体保护焊热丝法焊缝金属组织对力学性能的影响

• 发表时间: 2013
• 期刊: Tetsu-To-Hagane/Journal of the Iron and Steel Institute of Japan
• 作者: Tsuyama;T.;Nakai;K.;Kobayashi;S
• 通讯作者: S

Ti 合金インプラント周囲の生体骨組織の結晶学的解析

钛合金种植体周围活骨组织的晶体学分析

• 发表时间: 2014
• 作者: 山口敏郎;松峯昭彦;長谷川正裕;中村知樹;須藤啓広 .;和田祐典
• 通讯作者: 和田祐典