课题基金 / 基金详情

A chemokine receptor as a novel treatment target of age-related macular degeneration,

A chemokine receptor as a novel treatment target of age-related macular degeneration,
趋化因子受体作为年龄相关性黄斑变性的新治疗靶点,
批准号:
23592552
负责人:
YANAGI Yasuo
金额:
$3.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

项目摘要

项目成果

YANAGI Yasuo的其他基金

相似基金

相关文献

中文摘要
翻译
本研究探讨炎症细胞因子IP-10对年龄相关性黄斑变性所致脉络膜新生血管的影响。结果表明IP-10在炎症巨噬细胞和视网膜色素上皮细胞中产生,并通过其受体CXCR 3抑制脉络膜新生血管形成。本研究为老年性黄斑变性(一种导致法律的失明的毁灭性疾病)确定了一个新的治疗靶点。
英文摘要
This study investigated the effects of inflammatory cytokine, IP-10, on choroidal neovascularization due to age-related macular degeneration. The results demonstrated that IP-10 is produced in the inflammatory macrophage and retinal pigment epithelial cells and inhibits choroidal neovascularization through its receptor, CXCR3.This study identified a new treatment target for age-related macular degeneration, a devastating condition leading to legal blindness.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1167/iovs.11-8232
发表时间: 2012-04-01
期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
影响因子: 4.4
作者: [Fujimura, Shigeto, Takahashi, Hidenori, Yanagi, Yasuo]
通讯作者: Yanagi, Yasuo
Role of lipofuscin on retinal pigment epithelial cells and Bruch's membrane
  • 批准号:
    21791669
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.75万
  • 财政年份:
    2009
  • 负责人:
    YANAGI Yasuo
  • 依托单位:
海外基金