The development of the cementum / periodontal membrane reproduction type implant with induced pluripotent stem cells derived from oral mucosa

在口腔内膜来源的 iPS 细胞、Emdogain 和 Matarigel 与 HAT-7 细胞共培养的情况下，iPS 细胞储备的细胞生长、形态改变、大鼠牙源性上皮细胞 (HAT-7) 表面 Pax 诱导因子的存在以及大鼠牙源性上皮细胞 (HAT-7) 表面 Pax9 的诱导活性被以下研究的揭示和共培养所接受： Msx1、Pax9和Lhx6是牙齿生成过程中揭示的转录因子。尽管使用抗体阵列和Bio-Plex悬浮阵列系统对Emdogain、Matigel和GFR Matarigel中含有的细胞生长因子进行了综合分析，但并未鉴定出细胞生长因子。

Under existence of a lining-of-the-mouth origin iPS cell, Emdogain, and Matarigel, in co-culture with HAT-7 cell, The cell growth of an iPS cell stock, altered morphology, And existence of the Pax inducing factor in the rat odontogenic epithelial cell (HAT-7) surface and the inducible activity of Pax9 in the rat odontogenic epithelial cell (HAT-7) surface were accepted by the revelation and co-culture of Msx1, Pax9, and Lhx6 which are the transcription factors revealed in a dental generating process.Although the cell growth factor contained in Emdogain, Matigel, and GFR Matarigel, was comprehensively analyzed using the antibody array and the Bio-Plex suspension array system, it did not result in identification of a cell growth factor.