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Gastric emptying rate in subjects with malocclusion examined by [13C] breath test

通过[13C]呼气试验检查咬合不正受试者的胃排空率

基本信息

批准号：
23593023
负责人：
FUKUYAMA Eiji
金额：
$ 3.33万
依托单位：
Tokyo Medical and Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2011
资助国家：
日本
起止时间：
2011 至 2013
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23593023/
关键词：
胃排出機能国際研究者交流

项目摘要

Masticatory function is significantly lower in individuals with malocclusion than in those with normal occlusion. Although several studies suggest that masticatory function influences gastrointestinal digestive function, the relationship between malocclusion and gastrointestinal symptoms has not been studied extensively. We hypothesized that insufficient masticatory function would increase the functional burden of the stomach and have some influence on the gastrointestinal system. The purpose of this study was to investigate masticatory function and gastric emptying rate in subjects with malocclusion. Eleven healthy dentate female volunteers and eleven female patients with malocclusion underwent a 13C-acetate breath test with a liquid meal. Maximum 13CO2 exhalation time (Tmax) was compared statistically between both groups. The mean Tmax of the malocclusion group was significantly longer than that of the normal occlusion group.

错牙合患者的咀嚼功能明显低于正常牙合患者。虽然一些研究表明咀嚼功能影响胃肠道消化功能，但错牙合畸形与胃肠道症状之间的关系尚未得到广泛研究。我们推测咀嚼功能不足会增加胃的功能负担，对胃肠系统产生一定的影响。本研究旨在探讨错牙合患者的咀嚼功能及胃排空率。11名健康的有齿女性志愿者和11名女性错牙合患者进行了13 C-醋酸呼气试验与液体餐。两组之间的最大13 CO2呼气时间（Tmax）进行了统计学比较。错牙合组的平均Tmax明显长于正常牙合组。