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An examination fat metabolism, arteriosclerosis profile and climacteric symptoms of menopausal women with lactation experience

有哺乳经历的更年期妇女脂肪代谢、动脉硬化特征及更年期症状的检查

基本信息

批准号：
23593323
负责人：
UMENO YOSHIE
金额：
$ 3.24万
依托单位：
Oita University of Nursing and Health Sciences
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2011
资助国家：
日本
起止时间：
2011 至 2013
项目状态：
已结题

项目摘要

The purpose of this study was to examine the proportion fat metabolism, arteriosclerosis profile, and the proportion of Simplified Menopause Index (SMI) scores in 39 women aged between 40 and 60 years from the general population, and to compare findings according to the presence or absence of lactation experience. Examined items were total cholesterol (T-cho), triglycerides (TG), pulse wave velocity (baPWV) ,hormone and SMI. The respondents were then further categorized for analysis based on experience of lactation. T-cho level was significantly lower in the menopause/lactation-experienced group than in the menopause/lactation-naive group (p = 0.048). The SMI of postmenopausal women with lactation experience tended to be low, and an association with fat metabolism was found. Based on these findings, lactation experience appeared to be associated with fat metabolism, arteriosclerosis, and climacteric symptoms in postmenopausal women.

本研究的目的是从普通人群中检测39名年龄在40-60岁之间的女性的脂肪代谢比例、动脉硬化情况和简化绝经指数(SMI)评分的比例，并根据是否有哺乳经历来比较研究结果。检查项目为总胆固醇(T-CHO)、甘油三酯(TG)、脉搏波传导速度(BaPWV)、激素和SMI。然后，根据哺乳经验对受访者进行进一步分类分析。绝经/哺乳经验组T-CHO水平显著低于绝经/哺乳期未育组(P=0.048)。有哺乳经历的绝经后妇女SMI偏低，且与脂肪代谢有关。根据这些发现，哺乳经历似乎与绝经后妇女的脂肪代谢、动脉硬化和更年期症状有关。