The influence on bone marrow cells of the indoor environment chemicals: Analysis of dendritic cell differentiation and the Treg induction

由于据报道，接触各种化学物质的儿童增加，我们调查了一种化学物质的影响，如甲醛和甲苯，这是怀疑特别是化学产前期的影响。考虑到暴露模型小鼠，出生后立即从暴露小鼠中制备胸腺细胞。此外，骨髓来源的细胞也高度活化，因此，低浓度的化学品产前暴露影响细胞的分子水平上的事件。

As it has been reported that exposure of a wide variety of chemical substances to the child was increased, we investigated the effect of a substance chemical, such as formaldehyde and toluene, which is suspected in particular the effect of chemical prenatal period. From consideration of the exposure model mice, thymocytes immediately prepared from exposed mice after birth. Additionally, bone marrow derived cells were also highly activated.Thus, the low concentration chemical prenatal exposure affected cellular events on the molecular level.