A suppression and separation method of the water solvent signal for the improvement of the accuracy and stability in noninvasive blood glucose measurement

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In a noninvasive blood glucose measurement based on a near infrared light, it is necessary to suppress the signal of the water solvent, which is the main causes of background noise, to improve the accuracy and stability of measurement. In this research, we proposed the method of measuring a glucose signal, irradiating a sample with the excitation light that has a wavelength corresponding to the maximum absorption of the water molecule. It was shown that the signal originated from the water molecule could be separated effectively, as a result of the fundamental experiment. Furthermore, it was shown clearly that glucose concentration could be estimated by about 10% of precision for measurement based on this method.