Nanoplasmonic gene gun

纳米等离子体基因枪

• 批准号: 23650310
• 负责人: TERAKAWA Mitsuhiro
• 金额: $ 2.25万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23650310/
• 关键词: 低侵襲治療システム; レーザー医療; レーザードラッグデリバリー; 増強局在近接場光

We proposed and demonstrated nanosphere propulsion by using femtosecond-laser excited enhanced near-field. Velocity, angle, and diameter of propelled nanospheres were investigated and high spatial controllability of the propulsion was demonstrated based on the FDTD calculation and experiments. Little structural change was observed after the propulsion, indicating the potentiality to the drug propulsion with less damage effect to the embedded molecules.

我们提出并证明了利用飞秒激光激发增强近场推进纳米球。基于FDTD计算和实验，研究了推进纳米球的速度、角度和直径，证明了推进的高度空间可控性。推进后结构变化不大，表明药物推进的潜力，对包埋分子的损伤较小。

项目成果

Gold nanosphere propulsion by using femtosecond laser-excited enhanced near field

• DOI: 10.1007/s00339-014-8328-0
• 发表时间: 2014-03
• 期刊: Applied Physics A
• 作者: T. Shinohara;M. Terakawa

The shape of nanospheres propelled by femtosecond laser-excited enhanced near field

飞秒激光激发增强近场驱动的纳米球形状

• 发表时间: 2014
• 作者: 伊良皆啓治;上原弦;内山剛;円福敬二;篠原拓也
• 通讯作者: 篠原拓也

レーザー励起局在増強近接場光による粒子推進を目指した光増強場解析

针对激光激发局部增强近场光粒子推进的光增强场分析

• 发表时间: 2012
• 作者: Izumi S et al.;篠原拓也
• 通讯作者: 篠原拓也

Toshiyuki Honda, Mitsuhiro Terakawa, Minoru Obara

本田敏之、寺川光宏、小原稔

• 发表时间: 2012
• 作者: Prapatsorn Techawanitchai;Mitsuhiro Ebara;Naokazu Idota;Takao Aoyagi;出江紳一;Enhanced near-field properties of a gap of TiO2 nanosphere pairs for 3D photocatalytic optical trap
• 通讯作者: Enhanced near-field properties of a gap of TiO2 nanosphere pairs for 3D photocatalytic optical trap

篠原拓也、小原豪、寺川光洋

筱原卓也、大原豪、寺川光宏

• 发表时间: 2012
• 作者: 森 宏仁;他;レーザー励起局在増強近接場光による粒子推進を目指した光増強場解析
• 通讯作者: レーザー励起局在増強近接場光による粒子推進を目指した光増強場解析