Development of a new health screening system for safer driving based oncardiovascular measurements in a finger using the volume-oscillometric principle

开发了一种简化的系统，用于从使用体积测量技术在手指中非侵入性地获得的心血管参数进行健康筛查，并进行了初步评估。自动化仪器同时测量关键心血管参数，包括血压、脉压、心率、标准化脉搏量（作为α-肾上腺素介导的交感神经活动的指标）和手指动脉弹性。我们在健康志愿者的日常生活中测试了一个原型仪器，包括睡眠剥夺作为生理挑战。总之，我们开发的系统可以方便快捷地定期收集生理数据，没有任何故障，证明了检测对健康不利影响的可能性。除了这项研究，血液酒精测量使用光学原理进行了研究，以减少健康和酒精相关的机动车事故作为新的车辆安全锁。

A simplified system for health screening from cardiovascular parameters obtained non-invasively in a finger using the volume-oscillometric technique was developed and its preliminary assessment was conducted. An automated instrument made simultaneous measurements of key cardiovascular parameters, including blood pressure, pulse pressure, heart rate, normalized pulse volume as an index of α-adrenalin-mediated sympathetic activity, and finger arterial elasticity. We tested a prototype instrument in healthy volunteers during day-to-day living, including a sleep deprivation as physiological challenge. In conclusion, the system we have developed has allowed the periodic collection of physiological data in a convenient and expeditious way without any failure, demonstratingthe possibility to detect an adverse effect on health. In addition to this study, blood alcohol measurement using the optical principle was investigated in order to reduce health- and alcohol-related motor vehicle accidents as novel vehicle safety-locks.